Research

Transcriptional enhancers in embryonic development

I am currently studying how enhancers encode precise tissue-specific expression.

Press:

Extra Fingers and Hearts: Pinpointing Changes to Our Genetic Instructions That Disrupt Development

Analyzing pathogenic MEK1 mutations in embryonic development

I demonstrated a ranking of MEK1 mutations found in RASopathies, which are a group of human developmental disorders, using functional assays in the embryonic zebrafish.

Press:

Fusion of multiple disciplines on display at Bioengineering Day

Studies point way to precision therapies for common class of genetic disorders

Labeling proteins with non-canonical amino acids

I assisted in describing a mutant murine methionyl-tRNA-synthetase that charges the noncanonical amino acid azidonorleucine to elongator tRNA^Met in hamster (CHO), monkey (COS7), and human (HeLa) cell lines.