Granton Jindal

Granton Jindal

Assistant Project Scientist at UC San Diego

Publications and preprints

  • Jindal GA, Lim F, Tellez K, Song BP, Bantle AT, Farley EK. Protocol to electroporate DNA plasmids into Ciona robusta embryos at the 1-cell stage. STAR Protocols. 5(3), 103107 (2024). link

  • Lim F*, Solvason JJ*, Ryan GE*, Le SH, Jindal GA, Steffen P, Jandu SK, Farley EK. Affinity-optimizing enhancer variants disrupt development. Nature (2024). link

  • Jindal GA, Bantle AT, Solvason JJ, Grudzien JL, D’Antonio-Chronowska A, Lim F, Le SH, Song BP, Ragsac MF, Klie A, Larsen RO, Frazer KA, Farley EK. Single nucleotide variants within heart enhancers dramatically increase binding affinity and disrupt heart development. Dev. Cell. 58:2206-2216 (2023). link

  • Song BP, Ragsac MF, Tellez K, Jindal GA, Grudzien JL, Le SH, Farley EK. Diverse logics and grammar encode notochord enhancers. Cell Reports 42, 112052 (2023). link

  • Marmion RA, Yang L, Goyal Y, Jindal GA, Wetzel JL, Singh M, Schüpbach T, Shvartsman SY. Molecular mechanisms underlying cellular effects of human MEK1 mutations. Mol. Biol. Cell. 32:974-983 (2021). link

  • Jindal GA and Farley EK. Enhancer grammar in development, evolution, and disease: dependencies and interplay. Dev. Cell. 56:575-587 (2021). link

  • Pelliccia JL, Jindal GA, Burdine RD. Gdf3 is required for robust Nodal signaling during germ layer formation and left-right patterning. eLife. 6:e28635 (2017). link

  • Jindal GA*, Goyal Y*, Humphreys JM, Yeung E, Tian K, Patterson VL, He H, Burdine RD, Goldsmith EJ#, Shvartsman SY#. How activating mutations affect MEK1 regulation and function. J. Biol. Chem. 292:18814-18820 (2017). link

  • Goyal Y*, Jindal GA*, Pelliccia JL, Yamaya K, Yeung E, Futran AS, Burdine RD, Schüpbach T, Shvartsman SY. Divergent effects of intrinsically active MEK variants on developmental Ras signaling. Nat. Genet. 49:465-469 (2017). link

  • Jindal GA*, Goyal Y*, Yamaya K, Futran AS, Kountouridis I, Balgobin CA, Schüpbach T, Burdine RD, Shvartsman SY. In vivo severity ranking of Ras pathway mutations associated with developmental disorders. Proc. Natl. Acad. Sci. U.S.A. 114:510-515 (2017). link

  • Mahdavi A, Hamblin GD, Jindal GA, Bagert JD, Dong C, Sweredoski MJ, Hess S, Schuman EM, Tirrell DA. An engineered aminoacyl-tRNA synthetase for cell-selective analysis of mammalian protein synthesis. J. Am. Chem. Soc. 138:4278-4281 (2016). link

  • Jindal GA*, Goyal Y*, Burdine RD, Rauen KA, Shvartsman SY. RASopathies: unraveling mechanisms with animal models. Dis. Model. Mech. 8:769-782 (2015). link

  • Mahdavi A, Segall-Shapiro TH, Kou S, Jindal GA, Hoff KG, Liu S, Chitsaz M, Ismagilov RF, Silberg JJ, Tirrell DA. A Genetically Encoded AND Gate for Cell-Targeted Metabolic Labeling of Proteins. J. Am. Chem. Soc. 135:2979-2982 (2013). link